CovidV2, Main, Exploration, bibRecord, 000746

First Case of 2019 Novel Coronavirus in the United States.

Identifieur interne : 000746 ( Main/Exploration ); précédent : 000745; suivant : 000747

First Case of 2019 Novel Coronavirus in the United States.

Auteurs : Michelle L. Holshue ; Chas Debolt ; Scott Lindquist ; Kathy H. Lofy ; John Wiesman ; Hollianne Bruce ; Christopher Spitters ; Keith Ericson ; Sara Wilkerson ; Ahmet Tural ; George Diaz ; Amanda Cohn ; Leanne Fox ; Anita Patel ; Susan I. Gerber ; Lindsay Kim ; Suxiang Tong ; Xiaoyan Lu ; Steve Lindstrom ; Mark A. Pallansch ; William C. Weldon ; Holly M. Biggs ; Timothy M. Uyeki ; Satish K. Pillai

Source :

The New England journal of medicine [ 1533-4406 ] ; 2020.

RBID : pubmed:32004427

Descripteurs français

KwdFr :
- Adulte, Analyse chimique du sang, Analyse de séquence d'ADN, Chine, Génome viral, Humains, Infections à coronavirus (), Infections à coronavirus (diagnostic), Infections à coronavirus (transmission), Mâle, Pneumopathie virale (), Pneumopathie virale (diagnostic), Pneumopathie virale (transmission), Poumon (anatomopathologie), Poumon (imagerie diagnostique), Radiographie thoracique, Voyage, États-Unis d'Amérique, Évolution de la maladie.
MESH :
- anatomopathologie : Poumon.
- diagnostic : Infections à coronavirus, Pneumopathie virale.
- imagerie diagnostique : Poumon.
- Adulte, Analyse chimique du sang, Analyse de séquence d'ADN, Chine, Génome viral, Humains, Infections à coronavirus, Mâle, Pneumopathie virale, Radiographie thoracique, Voyage, États-Unis d'Amérique, Évolution de la maladie.
Wicri :
- geographic : République populaire de Chine, États-Unis.

English descriptors

KwdEn :
- Adult, Betacoronavirus (genetics), Betacoronavirus (isolation & purification), Blood Chemical Analysis, China, Coronavirus Infections (diagnosis), Coronavirus Infections (therapy), Coronavirus Infections (transmission), Disease Progression, Genome, Viral, Humans, Lung (diagnostic imaging), Lung (pathology), Male, Pneumonia, Viral (diagnosis), Pneumonia, Viral (therapy), Pneumonia, Viral (transmission), Radiography, Thoracic, Sequence Analysis, DNA, Travel, United States.
MESH :
- geographic : China, United States.
- diagnosis : Coronavirus Infections, Pneumonia, Viral.
- diagnostic imaging : Lung.
- genetics : Betacoronavirus.
- isolation & purification : Betacoronavirus.
- pathology : Lung.
- therapy : Coronavirus Infections, Pneumonia, Viral.
- transmission : Coronavirus Infections, Pneumonia, Viral.
- Adult, Blood Chemical Analysis, Disease Progression, Genome, Viral, Humans, Male, Radiography, Thoracic, Sequence Analysis, DNA, Travel.

Abstract

An outbreak of novel coronavirus (2019-nCoV) that began in Wuhan, China, has spread rapidly, with cases now confirmed in multiple countries. We report the first case of 2019-nCoV infection confirmed in the United States and describe the identification, diagnosis, clinical course, and management of the case, including the patient's initial mild symptoms at presentation with progression to pneumonia on day 9 of illness. This case highlights the importance of close coordination between clinicians and public health authorities at the local, state, and federal levels, as well as the need for rapid dissemination of clinical information related to the care of patients with this emerging infection.

DOI: 10.1056/NEJMoa2001191
PubMed: 32004427

Affiliations:

Le document en format XML

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<author><name sortKey="Holshue, Michelle L" sort="Holshue, Michelle L" uniqKey="Holshue M" first="Michelle L" last="Holshue">Michelle L. Holshue</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
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<author><name sortKey="Debolt, Chas" sort="Debolt, Chas" uniqKey="Debolt C" first="Chas" last="Debolt">Chas Debolt</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
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<author><name sortKey="Lindquist, Scott" sort="Lindquist, Scott" uniqKey="Lindquist S" first="Scott" last="Lindquist">Scott Lindquist</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
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</author>
<author><name sortKey="Lofy, Kathy H" sort="Lofy, Kathy H" uniqKey="Lofy K" first="Kathy H" last="Lofy">Kathy H. Lofy</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Wiesman, John" sort="Wiesman, John" uniqKey="Wiesman J" first="John" last="Wiesman">John Wiesman</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Bruce, Hollianne" sort="Bruce, Hollianne" uniqKey="Bruce H" first="Hollianne" last="Bruce">Hollianne Bruce</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Spitters, Christopher" sort="Spitters, Christopher" uniqKey="Spitters C" first="Christopher" last="Spitters">Christopher Spitters</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Ericson, Keith" sort="Ericson, Keith" uniqKey="Ericson K" first="Keith" last="Ericson">Keith Ericson</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Wilkerson, Sara" sort="Wilkerson, Sara" uniqKey="Wilkerson S" first="Sara" last="Wilkerson">Sara Wilkerson</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Tural, Ahmet" sort="Tural, Ahmet" uniqKey="Tural A" first="Ahmet" last="Tural">Ahmet Tural</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Diaz, George" sort="Diaz, George" uniqKey="Diaz G" first="George" last="Diaz">George Diaz</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Cohn, Amanda" sort="Cohn, Amanda" uniqKey="Cohn A" first="Amanda" last="Cohn">Amanda Cohn</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Fox, Leanne" sort="Fox, Leanne" uniqKey="Fox L" first="Leanne" last="Fox">Leanne Fox</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Patel, Anita" sort="Patel, Anita" uniqKey="Patel A" first="Anita" last="Patel">Anita Patel</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Gerber, Susan I" sort="Gerber, Susan I" uniqKey="Gerber S" first="Susan I" last="Gerber">Susan I. Gerber</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Kim, Lindsay" sort="Kim, Lindsay" uniqKey="Kim L" first="Lindsay" last="Kim">Lindsay Kim</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Tong, Suxiang" sort="Tong, Suxiang" uniqKey="Tong S" first="Suxiang" last="Tong">Suxiang Tong</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Lu, Xiaoyan" sort="Lu, Xiaoyan" uniqKey="Lu X" first="Xiaoyan" last="Lu">Xiaoyan Lu</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Lindstrom, Steve" sort="Lindstrom, Steve" uniqKey="Lindstrom S" first="Steve" last="Lindstrom">Steve Lindstrom</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Pallansch, Mark A" sort="Pallansch, Mark A" uniqKey="Pallansch M" first="Mark A" last="Pallansch">Mark A. Pallansch</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Weldon, William C" sort="Weldon, William C" uniqKey="Weldon W" first="William C" last="Weldon">William C. Weldon</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Biggs, Holly M" sort="Biggs, Holly M" uniqKey="Biggs H" first="Holly M" last="Biggs">Holly M. Biggs</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Uyeki, Timothy M" sort="Uyeki, Timothy M" uniqKey="Uyeki T" first="Timothy M" last="Uyeki">Timothy M. Uyeki</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Pillai, Satish K" sort="Pillai, Satish K" uniqKey="Pillai S" first="Satish K" last="Pillai">Satish K. Pillai</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2020">2020</date>
<idno type="RBID">pubmed:32004427</idno>
<idno type="pmid">32004427</idno>
<idno type="doi">10.1056/NEJMoa2001191</idno>
<idno type="wicri:Area/PubMed/Corpus">000C20</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000C20</idno>
<idno type="wicri:Area/PubMed/Curation">000C20</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000C20</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000692</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000692</idno>
<idno type="wicri:Area/Ncbi/Merge">000936</idno>
<idno type="wicri:Area/Ncbi/Curation">000936</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000936</idno>
<idno type="wicri:Area/Main/Merge">000748</idno>
<idno type="wicri:Area/Main/Curation">000746</idno>
<idno type="wicri:Area/Main/Exploration">000746</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">First Case of 2019 Novel Coronavirus in the United States.</title>
<author><name sortKey="Holshue, Michelle L" sort="Holshue, Michelle L" uniqKey="Holshue M" first="Michelle L" last="Holshue">Michelle L. Holshue</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Debolt, Chas" sort="Debolt, Chas" uniqKey="Debolt C" first="Chas" last="Debolt">Chas Debolt</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Lindquist, Scott" sort="Lindquist, Scott" uniqKey="Lindquist S" first="Scott" last="Lindquist">Scott Lindquist</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Lofy, Kathy H" sort="Lofy, Kathy H" uniqKey="Lofy K" first="Kathy H" last="Lofy">Kathy H. Lofy</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Wiesman, John" sort="Wiesman, John" uniqKey="Wiesman J" first="John" last="Wiesman">John Wiesman</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Bruce, Hollianne" sort="Bruce, Hollianne" uniqKey="Bruce H" first="Hollianne" last="Bruce">Hollianne Bruce</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Spitters, Christopher" sort="Spitters, Christopher" uniqKey="Spitters C" first="Christopher" last="Spitters">Christopher Spitters</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Ericson, Keith" sort="Ericson, Keith" uniqKey="Ericson K" first="Keith" last="Ericson">Keith Ericson</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Wilkerson, Sara" sort="Wilkerson, Sara" uniqKey="Wilkerson S" first="Sara" last="Wilkerson">Sara Wilkerson</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Tural, Ahmet" sort="Tural, Ahmet" uniqKey="Tural A" first="Ahmet" last="Tural">Ahmet Tural</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Diaz, George" sort="Diaz, George" uniqKey="Diaz G" first="George" last="Diaz">George Diaz</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Cohn, Amanda" sort="Cohn, Amanda" uniqKey="Cohn A" first="Amanda" last="Cohn">Amanda Cohn</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Fox, Leanne" sort="Fox, Leanne" uniqKey="Fox L" first="Leanne" last="Fox">Leanne Fox</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Patel, Anita" sort="Patel, Anita" uniqKey="Patel A" first="Anita" last="Patel">Anita Patel</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Gerber, Susan I" sort="Gerber, Susan I" uniqKey="Gerber S" first="Susan I" last="Gerber">Susan I. Gerber</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Kim, Lindsay" sort="Kim, Lindsay" uniqKey="Kim L" first="Lindsay" last="Kim">Lindsay Kim</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Tong, Suxiang" sort="Tong, Suxiang" uniqKey="Tong S" first="Suxiang" last="Tong">Suxiang Tong</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Lu, Xiaoyan" sort="Lu, Xiaoyan" uniqKey="Lu X" first="Xiaoyan" last="Lu">Xiaoyan Lu</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Lindstrom, Steve" sort="Lindstrom, Steve" uniqKey="Lindstrom S" first="Steve" last="Lindstrom">Steve Lindstrom</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Pallansch, Mark A" sort="Pallansch, Mark A" uniqKey="Pallansch M" first="Mark A" last="Pallansch">Mark A. Pallansch</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Weldon, William C" sort="Weldon, William C" uniqKey="Weldon W" first="William C" last="Weldon">William C. Weldon</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Biggs, Holly M" sort="Biggs, Holly M" uniqKey="Biggs H" first="Holly M" last="Biggs">Holly M. Biggs</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Uyeki, Timothy M" sort="Uyeki, Timothy M" uniqKey="Uyeki T" first="Timothy M" last="Uyeki">Timothy M. Uyeki</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Pillai, Satish K" sort="Pillai, Satish K" uniqKey="Pillai S" first="Satish K" last="Pillai">Satish K. Pillai</name>
<affiliation><nlm:affiliation>From the Epidemic Intelligence Service (M.L.H.), the National Center for Immunizations and Respiratory Diseases (A.C., L.F., A.P.), the Division of Viral Diseases (S.I.G., L.K., S.T., X.L., S. Lindstrom, M.A.P., W.C.W., H.M.B.), the Influenza Division (T.M.U.), and the Division of Preparedness and Emerging Infections (S.K.P.), Centers for Disease Control and Prevention, Atlanta; and the Washington State Department of Health, Shoreline (M.L.H., C.D., S. Lindquist, K.H.L., J.W.), Snohomish Health District (H.B., C.S.), Providence Medical Group (K.E.), and Providence Regional Medical Center (S.W., A.T., G.D.), Everett, and Department of Medicine, University of Washington School of Medicine, Seattle (C.S.) - all in Washington.</nlm:affiliation>
<wicri:noCountry code="subField">Seattle (C.S.)</wicri:noCountry>
</affiliation>
</author>
</analytic>
<series><title level="j">The New England journal of medicine</title>
<idno type="eISSN">1533-4406</idno>
<imprint><date when="2020" type="published">2020</date>
</imprint>
</series>
</biblStruct>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Betacoronavirus (genetics)</term>
<term>Betacoronavirus (isolation & purification)</term>
<term>Blood Chemical Analysis</term>
<term>China</term>
<term>Coronavirus Infections (diagnosis)</term>
<term>Coronavirus Infections (therapy)</term>
<term>Coronavirus Infections (transmission)</term>
<term>Disease Progression</term>
<term>Genome, Viral</term>
<term>Humans</term>
<term>Lung (diagnostic imaging)</term>
<term>Lung (pathology)</term>
<term>Male</term>
<term>Pneumonia, Viral (diagnosis)</term>
<term>Pneumonia, Viral (therapy)</term>
<term>Pneumonia, Viral (transmission)</term>
<term>Radiography, Thoracic</term>
<term>Sequence Analysis, DNA</term>
<term>Travel</term>
<term>United States</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term>
<term>Analyse chimique du sang</term>
<term>Analyse de séquence d'ADN</term>
<term>Chine</term>
<term>Génome viral</term>
<term>Humains</term>
<term>Infections à coronavirus ()</term>
<term>Infections à coronavirus (diagnostic)</term>
<term>Infections à coronavirus (transmission)</term>
<term>Mâle</term>
<term>Pneumopathie virale ()</term>
<term>Pneumopathie virale (diagnostic)</term>
<term>Pneumopathie virale (transmission)</term>
<term>Poumon (anatomopathologie)</term>
<term>Poumon (imagerie diagnostique)</term>
<term>Radiographie thoracique</term>
<term>Voyage</term>
<term>États-Unis d'Amérique</term>
<term>Évolution de la maladie</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en"><term>China</term>
<term>United States</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Poumon</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Infections à coronavirus</term>
<term>Pneumopathie virale</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Lung</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Betacoronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="imagerie diagnostique" xml:lang="fr"><term>Poumon</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Betacoronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Lung</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
</keywords>
<keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Blood Chemical Analysis</term>
<term>Disease Progression</term>
<term>Genome, Viral</term>
<term>Humans</term>
<term>Male</term>
<term>Radiography, Thoracic</term>
<term>Sequence Analysis, DNA</term>
<term>Travel</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte</term>
<term>Analyse chimique du sang</term>
<term>Analyse de séquence d'ADN</term>
<term>Chine</term>
<term>Génome viral</term>
<term>Humains</term>
<term>Infections à coronavirus</term>
<term>Mâle</term>
<term>Pneumopathie virale</term>
<term>Radiographie thoracique</term>
<term>Voyage</term>
<term>États-Unis d'Amérique</term>
<term>Évolution de la maladie</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>République populaire de Chine</term>
<term>États-Unis</term>
</keywords>
</textClass>
</profileDesc>
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<front><div type="abstract" xml:lang="en">An outbreak of novel coronavirus (2019-nCoV) that began in Wuhan, China, has spread rapidly, with cases now confirmed in multiple countries. We report the first case of 2019-nCoV infection confirmed in the United States and describe the identification, diagnosis, clinical course, and management of the case, including the patient's initial mild symptoms at presentation with progression to pneumonia on day 9 of illness. This case highlights the importance of close coordination between clinicians and public health authorities at the local, state, and federal levels, as well as the need for rapid dissemination of clinical information related to the care of patients with this emerging infection.</div>
</front>
</TEI>
<affiliations><list></list>
<tree><noCountry><name sortKey="Biggs, Holly M" sort="Biggs, Holly M" uniqKey="Biggs H" first="Holly M" last="Biggs">Holly M. Biggs</name>
<name sortKey="Bruce, Hollianne" sort="Bruce, Hollianne" uniqKey="Bruce H" first="Hollianne" last="Bruce">Hollianne Bruce</name>
<name sortKey="Cohn, Amanda" sort="Cohn, Amanda" uniqKey="Cohn A" first="Amanda" last="Cohn">Amanda Cohn</name>
<name sortKey="Debolt, Chas" sort="Debolt, Chas" uniqKey="Debolt C" first="Chas" last="Debolt">Chas Debolt</name>
<name sortKey="Diaz, George" sort="Diaz, George" uniqKey="Diaz G" first="George" last="Diaz">George Diaz</name>
<name sortKey="Ericson, Keith" sort="Ericson, Keith" uniqKey="Ericson K" first="Keith" last="Ericson">Keith Ericson</name>
<name sortKey="Fox, Leanne" sort="Fox, Leanne" uniqKey="Fox L" first="Leanne" last="Fox">Leanne Fox</name>
<name sortKey="Gerber, Susan I" sort="Gerber, Susan I" uniqKey="Gerber S" first="Susan I" last="Gerber">Susan I. Gerber</name>
<name sortKey="Holshue, Michelle L" sort="Holshue, Michelle L" uniqKey="Holshue M" first="Michelle L" last="Holshue">Michelle L. Holshue</name>
<name sortKey="Kim, Lindsay" sort="Kim, Lindsay" uniqKey="Kim L" first="Lindsay" last="Kim">Lindsay Kim</name>
<name sortKey="Lindquist, Scott" sort="Lindquist, Scott" uniqKey="Lindquist S" first="Scott" last="Lindquist">Scott Lindquist</name>
<name sortKey="Lindstrom, Steve" sort="Lindstrom, Steve" uniqKey="Lindstrom S" first="Steve" last="Lindstrom">Steve Lindstrom</name>
<name sortKey="Lofy, Kathy H" sort="Lofy, Kathy H" uniqKey="Lofy K" first="Kathy H" last="Lofy">Kathy H. Lofy</name>
<name sortKey="Lu, Xiaoyan" sort="Lu, Xiaoyan" uniqKey="Lu X" first="Xiaoyan" last="Lu">Xiaoyan Lu</name>
<name sortKey="Pallansch, Mark A" sort="Pallansch, Mark A" uniqKey="Pallansch M" first="Mark A" last="Pallansch">Mark A. Pallansch</name>
<name sortKey="Patel, Anita" sort="Patel, Anita" uniqKey="Patel A" first="Anita" last="Patel">Anita Patel</name>
<name sortKey="Pillai, Satish K" sort="Pillai, Satish K" uniqKey="Pillai S" first="Satish K" last="Pillai">Satish K. Pillai</name>
<name sortKey="Spitters, Christopher" sort="Spitters, Christopher" uniqKey="Spitters C" first="Christopher" last="Spitters">Christopher Spitters</name>
<name sortKey="Tong, Suxiang" sort="Tong, Suxiang" uniqKey="Tong S" first="Suxiang" last="Tong">Suxiang Tong</name>
<name sortKey="Tural, Ahmet" sort="Tural, Ahmet" uniqKey="Tural A" first="Ahmet" last="Tural">Ahmet Tural</name>
<name sortKey="Uyeki, Timothy M" sort="Uyeki, Timothy M" uniqKey="Uyeki T" first="Timothy M" last="Uyeki">Timothy M. Uyeki</name>
<name sortKey="Weldon, William C" sort="Weldon, William C" uniqKey="Weldon W" first="William C" last="Weldon">William C. Weldon</name>
<name sortKey="Wiesman, John" sort="Wiesman, John" uniqKey="Wiesman J" first="John" last="Wiesman">John Wiesman</name>
<name sortKey="Wilkerson, Sara" sort="Wilkerson, Sara" uniqKey="Wilkerson S" first="Sara" last="Wilkerson">Sara Wilkerson</name>
</noCountry>
</tree>
</affiliations>
</record>

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First Case of 2019 Novel Coronavirus in the United States.

First Case of 2019 Novel Coronavirus in the United States.

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